Radial Artery Tonometry Demonstrates Arterial Stiffness in Children With Type 1 Diabetes

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Radial artery tonometry demonstrates arterial stiffness in children with type 1 diabetes.

OBJECTIVE To determine if children with type 1 diabetes have increased arterial stiffness by estimating augmentation index with the simple noninvasive technique of radial artery tonometry. RESEARCH DESIGN AND METHODS We studied 98 type 1 diabetic children and 57 healthy control subjects, ages 10-18 years, matched for age, sex, race, and BMI, generating 43 matched pairs. Radial artery tonometr...

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Peripheral artery tonometry demonstrates altered endothelial function in children with type 1 diabetes.

OBJECTIVES To assess the ability of reactive hyperemia-peripheral artery tonometry (RH-PAT) to serve as a surrogate marker of endothelial dysfunction in children with type 1 diabetes (T1D). RESEARCH DESIGN AND METHODS Forty-four children with T1D [age 14.6 +/- 2.7 yr; duration of diabetes 6.01 +/- 4 yr; range of diabetes duration 1-16 yr; and hemoglobin A1c (HbA1c) 8.34 +/- 1.2%] and 20 child...

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NOS3 polymorphisms are associated with arterial stiffness in children with type 1 diabetes.

OBJECTIVE Type 1 diabetes is associated with endothelial dysfunction, arterial stiffness, and an increased risk of cardiovascular disease (CVD) events. We previously demonstrated increased arterial stiffness in children with type 1 diabetes compared with control subjects. However, traditional CVD risk factors did not explain the difference in arterial stiffness. Furthermore, children with type ...

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ژورنال

عنوان ژورنال: Diabetes Care

سال: 2004

ISSN: 0149-5992,1935-5548

DOI: 10.2337/diacare.27.12.2911